Major Revision: This section begins with an overview of immune-mediated eye disease, summarizing basic immunologic concepts, ocular immune responses and special topics in ocular immunology. Now includes an interactive uveitis diagnostic algorithm and a chapter covering scleritis. Discusses the clinical approach to uveitis and reviews noninfectious (autoimmune) and infectious forms of uveitis, with an expanded section on viral uveitis and material on infectious and noninfectious scleritis. Enhanced detection of infectious agents by immunologic and genetic methods and biologic therapeutics are detailed. Also covers endophthalmitis, masquerade syndromes, complications of uveitis and ocular aspects of AIDS. // Includes three fundamental surgical technique videos and one diagnostic video. Access the videos via QR codes. // Upon completion of Section 9, readers should be able to: *Identify general and specific pathophysiologic processes that affect the structure and function of the uvea, lens, intraocular cavities, retina, and other tissues in acute and chronic intraocular inflammation; *Differentiate and identify infectious and noninfectious uveitic entities; *Choose appropriate examination techniques and relevant ancillary studies based on whether an infectious or noninfectious cause is suspected. // About the BCSC: The Academy's Basic and Clinical Science CourseTM is ophthalmology s definitive source of clinical information. Practicing ophthalmologists and residents worldwide use the BCSC® to ensure the highest-quality patient care. Stay current with the ophthalmic reference that is vetted by 100+ ophthalmologists every year. // Each of the 13 volumes includes up-to-date clinical knowledge, concise information and tables, self-assessment questions with answers, photos and illustrations and opportunities for earning AMA PRA Category 1 CreditTM. // Beginning with the 2013-2014 edition, the Academy and the European Board of Ophthalmology (EBO) have partnered to make the BCSC the standard text for all European ophthalmology training programs. The EBO now recommends the BCSC as the primary educational resource for European trainees and ophthalmologists studying for the annual EBO Diploma Exam. // CME Information: The American Academy of Ophthalmology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. // The American Academy of Ophthalmology designates this enduring material for a maximum of 10 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.